Software

nullranges

• Modular package for generation of sets of ranges representing the null hypothesis. These can take the form of bootRanges, block bootstrap samples of ranges, or matchRanges, sets of control ranges that are matched across one or more covariates. Developed by Wancen Mu, Eric Davis, and Douglas Phanstiel (UNC-CH). Contributions from other Bioconductor developers as well. Funding provided by CZI EOSS award.

airpart

• Identification of differential cell-type-specific allelic imbalance across cell types or states, utilizing single-cell allelic counts. Provides partitioning of cell types by allelic signal using generalized fused lasso, plus many EDA and QC plotting functions. Developed by Wancen Mu, in collaboration with the Patro group (UMD) and KB Choi (JAX).